Automated Calculation of Retinal Arteriovenous Ratio for Detection and Monitoring of Cerebrovascular Disease Based on Assessment of Morphological Changes of Retinal Vascular System
نویسندگان
چکیده
In the frame of the ARIC study it could be shown that the retinal vessel system gives important information about retinal, ophthalmic, and cerebrovascular diseases by manually labeling the vessels. In this paper an approach is presented which automatically assesses the retinal vessel systems in fundus images. For this, first the optic disk is located. Afterwards the vessels are segmented and then classified into arteries and veins. In the last step an index, based on the ratio of the diameters of arteries and veins, for the risk of suffering a stroke is calculated. Introduction/Mot ivation According to the WHO stroke is the second frequent cause of death world-wide. In Germany stroke is the third frequent cause of death and the most frequent reason for disability within adults. The treatment of stroke costs 15% of the yearly budget in public health in Germany and there are 180 primary strokes per 100.000 inhabitants each year. So there is a need for a primary stroke prevention in order to decrease the incidence. It is well known that morphological and functional changes in the retinal vessel system are risk indicators for cerebral arteriosclerosis. Using a new quantitative assessment of the retinal vessels a risk-index of stroke, based on morphological parameters, was developed by the ophthalmology group of the Atherosclerosis Risk in Communities Study (ARIC) [I], under the use of conventional ophthalmologic fundus images, which were assessed manually. In our approach a remote risk evaluation for stroke is facilitated by analysing the images of the retinal vessels captured with a non-mydriatic fundus camera automatically. Making this possible, the vessel system of the retina is automatically segmented and classified into arteries and veins. Morphological parameters for the retinal vessels are determined and a risk-index, based on the ratio of arteriolar diameter and venous diameter, is calculated. Using this system it is possible to identify persons with an elevated risk of stroke 'Address: HaberstraUe 2, 91058 Erlangen, Germany. E-mail:
منابع مشابه
Morphological Exudate Detection in Retinal Images using PCA-based Optic Disc Removal
Diabetic retinopathy lesion detection such as exudate in fundus image of retina can lead to early diagnosis of the disease. Retinal image includes dark areas such as main blood vessels and retinal tissue and also bright areas such as optic disk, optical fibers and lesions e.g. exudate. In this paper, a multistage algorithm for the detection of exudate in foreground is proposed. The algorithm se...
متن کاملMorphological changes in injured retinal pigment epithelium and photoreceptor cells after transplantation of stem cells into subretinal space
Introduction: Degenerative retinal diseases are main cause of irreversible blindness. Stem cells therapy is a promising way in these diseases. Therefore, mesenchymal stem cells because of its safety can produce degenerated cells and can play important role in treatment. The aim of this study was to examine morphological changes in injured retinal pigment epithelium (RPE) and photoreceptor cells...
متن کاملDetection of Microaneurysms in Retinal Angiography Images Using the Circular Hough Transform
This paper presents an automated method for detecting microaneurysms in the retinal angiographic images by using image processing techniques. In the presented method, in order to fade or remove the pseudo images, first retinal images are pre-processed. Then microaneurysms are identified by circular Hough transform. In the existing methods of dete...
متن کاملDetection of Microaneurysms in Retinal Angiography Images Using the Circular Hough Transform
This paper presents an automated method for detecting microaneurysms in the retinal angiographic images by using image processing techniques. In the presented method, in order to fade or remove the pseudo images, first retinal images are pre-processed. Then microaneurysms are identified by circular Hough transform. In the existing methods of dete...
متن کاملRetinal Microvascular Response to Short-Term Exposure to Particulate Matters As an Indicator of Cardiovascular Effects in Work Environments
Introduction: According to the literature, Central Retinal Arteriolar Equivalent (CRAE), Central Retinal Venular Equivalent (CRVE), and Artemio Venule Ratio (AVR) are three important markers in determining the changes of retinal artery. These markers are employed as an indicator of cardiovascular effects in workers. This study aimed to evaluate the changes in retinal micro vascular responses in...
متن کامل